Herbal Drug Industry

                              
                                      AS per PCI Syllabus


(T. Y.  B. Pharm Sem IV) Unit -V


Present scope of herbal drug industry

Herbs have been known since the era of civilizations and are highly esteemed all over the world as a rich source of medicinal agents. 

The popularity of natural products is increasing day by day due to the facts that they are comparatively safe, less toxic, less side effects, easily available and affordable prices when compared to synthetic drugs.

The herbal drug industry is a very fast growing sector in the international market. In India, various system of medicine like Ayurveda, Siddha, Unani, homeopathy, Yoga & Naturopathy are being utilized for the health care of people.

SCOPE OF HERBAL DRUG MEDICINE AND INDUSTRY

Indian herbal market

Herbal drugs constitute a major share of all the officially recognised systems of health in India viz. Ayurveda, Yoga, Unani, Siddha, Homeopathy and Naturopathy, except Allopathy. 

More than 70% of India's 1.1 billion populations still use these non-allopathic systems of medicine. Currently, there is no separate category of herbal drugs or dietary supplements, as per the Indian Drugs Act.

However, there is a vast experiential-evidence base for many of the natural drugs.

In India, raw drugs obtained from around 2,400 plant species. It is the fastest growing market & may attain to 14,500 crore & exports to 9000 crore with a CAGR (compound annual growth rate) of 20 % & 25% respectively, according to Associated Chambers of Commerce & Industry of India (Assocham).

The 'Herbal Industry Biz' has revealed that currently, the Indian herbal market size is estimated at 7000 crores & over 3600 crores of herbal raw materials & medicine are exported by India. 

In India, there are about 8000 medicinal plants are used. Out of which 25 manufacturers are large scale manufacturers. The annual turnover in India was around US $ 300 million for Ayurvedic & US $ 27.7 million for Unani medicine.

International scope of herbal medicines

According to the World Health Organization (WHO), approximately 25 per cent of modern drugs used in the United States have been derived from plants. 

More than 120 active compounds isolated from higher plants are widely used in modern allopathic medicine today and 80% of them show a positive co-relation between their modern therapeutic use and the traditional use of the plants from which they are derived. 

At least 7,000  medicinal compounds derived from plants, the ingredients of herbal medicine, are included in the modern pharmacopoeia of drugs.

WHO estimates that 80 per cent of the world's population currently use herbal medicines for some aspects of primary health care.
They are also highly lucrative in the international market, generating billions of dollars in revenue.
To cite a few examples, annual revenue from herbal medicines and herbal products in Western Europe reached US$ 5 billion in 2003-2004 In China, sales of herbal products totaled USS 14 billion in 2005.
Herbal medicine revenue in Brazil was USS 160 million in 2007.




Herbal medicine-based Traditional Medical system of treatment is a rapidly growing healthcare system of economic importance and is now widely used in many countries of the world. The following leads and developments are the future prospects in the herbal drug industry.

*   Plant products can also be useful as starting material for the semi synthetic preparation of other drugs. Examples: Plant steroids (Diosgenin): Oral contraceptives, hormones. Microrganisms (Streptomyces genus): Antibiotics  (Streptomycin, neomycin, tetracycline, chloramphenicol).

*   The interest in natural products as a source of new biologically active compounds has expanded due to increasing research and development in phytochemistry.

Note: Source of data: As per Associated chamber of Commerce & Industry (ASSOCHAM).

It has been estimated that 56% of the lead compounds for medicines in British National Formulary are natural products or are derived from them.

With the development in the techniques of molecular biology, there has been an increase of interest in the use of naturally occurring proteins as potential therapeutic agents. 

Several genetically engineered natural products have had a significant impact and more than 20 biotechnology derived products are now in the market.

Example: tissue plasminogen activator is used as a thrombolytic after myocardial infarctions Erythropoietin is used to treat anaemia associated with renal failure.
*   Several colony stimulating factors are used for cancer treatment. 
*   Natural products will continue to be important in the following three areas of drug discovery.
    qAs targets for production by biotechnology.
    qAs a source of new lead compds of novel chemical structure.
    qAs the active ingredients for useful treatments derived from traditional systems of medicine.
    In the face of the increasing use and fast-growing market of herbal medicines and other herbal healthcare products, in both developing and developed countries of the world, policy-makers, health professionals and the public are increasingly expressing concerns about the safety, efficacy, quality, availability, preservation, and further development problems of these herbal products. Public demand has also grown for evidence on the safety, efficacy and quality of herbal products and traditional medicine (TM) and complimentary alternative medicine(CAM) practices
   
   However, in order to ensure quality and safety of herbal medicines, their production, sale and use should be officially and legally controlled by established rules and regulations so that herbal medicines can be used safely for medical and therapeutic purposes and efforts should be made to raise public awareness about the risks and benefits of using herbal medicines.

Overview on Plant Based Industries and Research  

Institutions in India

List of research institutions and centres in India  

 Government of India also has expressed support and encouragement for the Traditional Indian Medicine (TIM). A separate department for Indian Systems of Medicine and Homeopathy now known as AYUSH (Ayurveda, Yoga, Unani, Siddha, Homoeopathy) was established in March 1995 to promote indigenous systems. 

Priorities include education, standardization of drugs, enhancement of availability of raw materials, research and development, information, communication and larger involvement in the national system for delivering health care.
In   the year 1969, the Indian government established a central council for research in Indian medicine and homeopathy (CCRIMH) to develop scientific research in different systems of medicine. As the research in herbal products expanded various government and private research centres developed which are actively engaged in the research and development of herbal medicines.
     
     The following are the list of few research institutions engaged in research in medicinal and aromatic plants in India.







  Thank You